Philadelphia chromosome
常见例句
- The Philadelphia chromosome (universally present in CML) is lacking in patients with leukemoid reactions.
费城染色体(一般出现在CML)在白血病样反应中一般不出现。
www.goo--gle.com - Philadelphia chromosome formed may result in the generation of the fusion protein BCR ABL, a constitutively activated tyrosine ki nas e which then causes chronic myeloid leukemia (CML).
慢性粒细胞白血病(CML)患者体内有异常染色体形成并产生BCR ABL融合蛋白,该融合蛋白能激活酪氨酸激酶,刺激细胞过度增生导致慢性粒细胞白血病的发生。 - The drug was originally developed as Imatinib using rational drug design after Philadelphia chromosome mutation was discovered.
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