Braf
基本解释
- 布拉夫
英汉例句
- Mutational activation of the BRAF oncogene is the most common genetic alteration in cutaneous melanoma.
BRAF癌基因突变的激活是皮肤黑色素瘤最常见的基因改变。 - BRAF related molecules in MAPK signal transduction are potential treatment target of MM.
BRAF突变相关的MAPK信号传导分子是治疗恶性黑素瘤的靶点。 - The BRAF mutation found in nevi and melanoma increases the activity of the BRAF protein, prompting cells to multiply abnormally.
BRAF蛋白在调控生长以及分化的信号通路中有重要的作用。而这种突变使得BRAF蛋白的活性增强，进而加速了异常的增殖。 - It's still controversial about the relationship of BRAF mutation with heredity, pre-existing pigment nevi, invasion and prognosis of MM.
此突变与遗传、预先存在的色素痣、肿瘤侵袭性及预后之间的关系还存在争论。 - It is recognized now that RAS, ERK, especially BRAF kinase in the MAPK/ERK pathway probably play important roles in the development of MM.
目前认为,该信号转导路径中的RAS、ERK,尤其是BRAF激酶在黑素瘤的发生发展中可能有重要作用。